ABC transporters affect the detection of intracellular oxidants by fluorescent probes.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00050241" target="_blank" >RIV/00216224:14310/11:00050241 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.3109/10715762.2011.579120" target="_blank" >http://dx.doi.org/10.3109/10715762.2011.579120</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/10715762.2011.579120" target="_blank" >10.3109/10715762.2011.579120</a>

Result language
angličtina
Original language name
ABC transporters affect the detection of intracellular oxidants by fluorescent probes.
Original language description
Intracellular production of reactive oxygen species (ROS) plays an important role in the control of cell physiology. For the assessment of intracellular ROS production, a plethora of fluorescent probes is commonly used. Interestingly, chemical structuresof these probes imply they could be substrates of plasma membrane efflux pumps, called ABC transporters. This study tested whether the determination of intracellular ROS production and mitochondrial membrane potential by selected fluorescent probes is modulated by the expression and activity of ABC transporters.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
—

Project
<a href="/en/project/GA301%2F08%2F0717" target="_blank" >GA301/08/0717: Gp130 receptor-mediated differentiation of ES cells</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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