Study of ergosterol signal pathway
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00050628" target="_blank" >RIV/00216224:14310/11:00050628 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Study of ergosterol signal pathway
Original language description
Ergosterol principal compound of the fungal plasma membrane belongs to the group of elicitors called non-specific elicitors whose not differ in their effects on different cultivars within a plant species. It triggers a defence reaction in tobacco and tomato cells manifested by active oxygen species synthesis and changes of ion fluxes. Further production of the phytoalexin capsidiol and pathogenesis related proteins expression was observed. Even though some steps of signalling pathway including phospholipase A2 protein kinase C and intracellular calcium were proposed up today activation mechanism was not elucidate. But it is assumed role of some specific binding partner or lipid rafts. Here we have attempted to elucidate in more details of the signal pathway elicited by ergosterol. Therefore we focused on study of calcium signalling by using fluorescence confocal microscopy and specific inhibitors.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CE - Biochemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů