Amplification of hTERC (3q26) and MYCC (8q24) genes in correlation with oncogenic human papilloma virus infection in cervical cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F11%3A00055260" target="_blank" >RIV/00216224:14310/11:00055260 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Amplification of hTERC (3q26) and MYCC (8q24) genes in correlation with oncogenic human papilloma virus infection in cervical cancer
Original language description
Cervical cancer remains one of the most common malignancies among women worldwide in both incidence and mortality. Several premalignant stages can be distinguished in the development of invasive carcinoma, including cervical intraepithelial neoplasia grades I-III (CIN I?III). The genetic basis of progression of CIN I to CIN II/III and to invasive carcinoma remain poorly understood. Although infection of high-risk human papilloma virus (HPV) is recognized as an essential initiating event in cervical tumorigenesis, this alone is not sufficient for the progression to invasive cancer. Some chromosomal aberrations have been associated with the progression of CIN to carcinoma, especially the amplification of the human telomerase gene hTERC (3q26) and protooncogene MYCC (8q24).
Czech name
—
Czech description
—
Classification
Type
O - Miscellaneous
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
—
Result continuities
Project
—
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů