Life cycle of Cryptosporidium muris in experimental conditions

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00058216" target="_blank" >RIV/00216224:14310/12:00058216 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Life cycle of Cryptosporidium muris in experimental conditions
Original language description
Cryptosporidia (Apicomplexa) have been recently recognized as one of the most ubiquitous parasites infecting gastrointestinal and respiratory tract of vertebrates. Localization of cryptosporidian developmental stages in the host epithelium has been the subject of extensive speculation for many years. Our published data support the term epicellular to reflect the cryptosporidian localization, rather than the term intracellular extracytoplasmic, used throughout the literature. Due to its peculiar localization, Cryptosporidium can derive nutrition while minimizing immunologic recognition and there is currently no effective treatment for cryptosporidiosis. In presented study, the life cycle of Cryptosporidium muris parasitizing gastric glands of experimentally infected laboratory rodents, Mastomys natalensis and BALB/c mice, has been analysed in detail. The main aim was to map the development of C. muris in hosts exhibiting different response to the parasitization.
Czech name
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Czech description
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Project
<a href="/en/project/GPP506%2F10%2FP372" target="_blank" >GPP506/10/P372: Comparative morphology and immunohistochemistry in the evaluation of phylogenetic affinities among early emerging apicomplexans</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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