PREPARATION OF APOFERRITIN SILVER PHOSPHATE NANOPARTICLES

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00060098" target="_blank" >RIV/00216224:14310/12:00060098 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
PREPARATION OF APOFERRITIN SILVER PHOSPHATE NANOPARTICLES
Original language description
Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for several difficult-to-treat infections in humans. Therefore, it is not surprising that other ways how to treat these bacteria are looked for. Silver(I) ions and silver nanoparticles exhibited the highest antimicrobial activity against MRSA but their transporting to the place of needs and in situ determination is an issue. We studied the encapsulation of silver(I) ions into apoferritin as a possible way for transportation of these ions.Primarily we optimized the encapsulation conditions to prepare the most stable complex, which was subsequently utilized for treatment of S. aureus. Based on the results obtained it can be concluded that silver(I) ions remain enclosed in the apoferritinstructure until decomposition of apoferritin by bacterial enzymatic apparatus occurs.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
XII. Pracovní setkání fyzikálních chemiků a elektrochemiků. Sborník příspěvků.
ISBN
9788073756185
ISSN
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e-ISSN
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Number of pages
3
Pages from-to
150-152
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Jan 1, 2012
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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