Diffusion Characteristics of Chlorine and Methoxy Derivatives of 6-benzylaminopurine Studied by Voltammetric Methods

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F12%3A00060137" target="_blank" >RIV/00216224:14310/12:00060137 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Diffusion Characteristics of Chlorine and Methoxy Derivatives of 6-benzylaminopurine Studied by Voltammetric Methods
Original language description
The metal complexes of chlorinated and methoxylated derivatives of 6 - benzylaminopurine (6-BAP) can be used as potential antineoplastic agents. From this point of view, the knowledge of the ability of these substances to diffuse into the intracellular area is very important. This property is characterized by the diffusion coefficient. The aim of our research is to determine the diffusion coefficients D of 6-BAP and its derivatives in buffered solutions (pH 3.21) containing 10% v/v CH3OH for two ionic strengths. Using the Delahay equation involving the reduction peaks of BAP derivatives on mercury electrode we calculated D and the charge transfer coefficient alpha we obtained from the elimination functions E1 and E4. The effect of some experimental parameters on D values was monitored.
Czech name
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Czech description
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Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
XXXII. Moderní elektrochemické metody. Sborník přednášek.
ISBN
9788090522107
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
112-116
Publisher name
BEST Servis
Place of publication
Ústí nad Labem
Event location
Jetřichovice
Event date
Jan 1, 2012
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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