Monogenean bioactive molecules at the parasite-host interface

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00066900" target="_blank" >RIV/00216224:14310/13:00066900 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Monogenean bioactive molecules at the parasite-host interface
Original language description
Hematophagous parasites have to avoid the host's hemostasis (blood coagulation) to facilitate blood intake. Therefore, they release anticoagulant peptides and anti-platelet aggregation agents into the site of feeding. These are usually produced by specialized glands and inhibit thrombosis and clot formation in the host. Antihemostatic molecules often act as protease inhibitors that target one or more serine proteases comprising the coagulation cascade. Protease inhibitors can be involved also in regulation of other biological processes, e.g., the course of host immune response. Transcriptome project on the haematophagous diplozoid monogenean Eudiplozoon nipponicum rendered view on the spectrum of bioactive molecules which can be involved in manipulation of host?s physiological processes by the parasite.
Czech name
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Czech description
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Project
<a href="/en/project/GAP506%2F12%2F1258" target="_blank" >GAP506/12/1258: Host-parasite interactions in blood-feeding diplozoid monogeneans: Investigation of highly specialized adaptation for parasitism</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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