Strategies for Stabilization and Activation of Biocatalysts in Organic Solvents

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00067016" target="_blank" >RIV/00216224:14310/13:00067016 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1021/cs400684x" target="_blank" >http://dx.doi.org/10.1021/cs400684x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/cs400684x" target="_blank" >10.1021/cs400684x</a>

Result language
angličtina
Original language name
Strategies for Stabilization and Activation of Biocatalysts in Organic Solvents
Original language description
One of the major barriers to the use of enzymes in industrial biotechnology is their insufficient stability under processing conditions. The use of organic solvent systems instead of aqueous media for enzymatic reactions offers numerous advantages, suchas increased solubility of hydrophobic substrates or suppression of water-dependent side reactions. For example, reverse hydrolysis reactions that form esters from acids and alcohols can become thermodynamically favourable in organic solution. However, organic solvents often inactivate enzymes. Industry and academia have devoted considerable effort into developing effective strategies to enhance the lifetime of enzymes in the presence of organic solvents.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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