Genome-wide transcriptional analysis upon entomopathogenic nematode infection of Drosophila
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F13%3A00069822" target="_blank" >RIV/00216224:14310/13:00069822 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Genome-wide transcriptional analysis upon entomopathogenic nematode infection of Drosophila
Original language description
Entomopathogenic nematodes (EPN) Heterorhabditis bacteriophora are obligate and lethal insect parasites. These EPN are symbiotically associated with entomopathogenic bacteria Photorhabdus luminescens creating the highly pathogenic nematobacterial complexthat is able to kill the host within 24 to 48 hours. H. bacteriophora with its bacterial symbionts are able to infect a broad spectrum of insect species. Symbiotic bacteria help to digest host tissues and provide nutrients for themselves and developingnematodes. Drosophila larvae are suitable insect hosts and part of the tripartite model system (Drosophila ? EPN - bacteria). In this study we examined transcriptional changes in Drosophila upon nematode infection. We compare gene expression in non- infected and infected fly larvae. We focused on the early time point of nematode infection and therefore infected Drosophila larvae using H. bacteriophora harbouring GFP-labelled P. luminescens bacteria.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů