MALDI-TOF fingerprinting of the whole mammalian cell-lines
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00078221" target="_blank" >RIV/00216224:14310/14:00078221 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
MALDI-TOF fingerprinting of the whole mammalian cell-lines
Original language description
Robust cell-lines identification requires reliable databases of cell-lines fingerprints. Mass spectrometric fingerprinting of mammalian cell-lines is a promising way to achieve the goal of fast, cheap, simple and reliable cell-lines authentication. However, general and standardized method for mass spectrometric fingerprinting of the whole mammalian cell-lines is not available to date. We developed, optimized and validated MALDI-TOF mass spectrometric method for reliable, specific and reproducible whole-cell fingerprinting of mammalian cell-lines. Quality and robustness of mass spectrometric fingerprints is demonstrated by statistical analysis of experimental data. Developed method for the whole mammalian cell-lines fingerprinting, in contrast to actualprocedures, is inexpensive, fast and it opens the door towards routine cell authentication.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED2.1.00%2F03.0086" target="_blank" >ED2.1.00/03.0086: Regional R&D center for low-cost plasma and nanotechnology surface modifications</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů