Deiodinases and thyroid metabolism disruption in teleost fish
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00079395" target="_blank" >RIV/00216224:14310/14:00079395 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0013935114003314" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0013935114003314</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.envres.2014.09.022" target="_blank" >10.1016/j.envres.2014.09.022</a>
Alternative languages
Result language
angličtina
Original language name
Deiodinases and thyroid metabolism disruption in teleost fish
Original language description
Many xenobiotic compounds with endocrine disrupting activity have been described since the late eighties. These compounds are able to interact with natural hormone systems and potentially induce deleterious effects in wildlife, notably piscine species. However, while the characterization of endocrine disruptors with "dioxin-like", estrogenic or androgenic activities is relatively well established, little is known about environmentally relevant pollutants that may act at thyroid system level. Iodothyronine deiodinases, the key enzymes in the activation and inactivation of thyroid hormones, have been suggested as suitable biomarkers for thyroid metabolism disruption. The present article reviews the biotic and abiotic factors that are able to modulate deiodinases in teleosts, a representative model organism for vertebrates.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DB - Geology and mineralogy
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Environmental Research
ISSN
0013-9351
e-ISSN
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Volume of the periodical
135
Issue of the periodical within the volume
NOV 2014
Country of publishing house
US - UNITED STATES
Number of pages
15
Pages from-to
361-375
UT code for WoS article
000346622800048
EID of the result in the Scopus database
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