The possible relationship between PAX9 gene polymorphisms and tooth agenesis in the Czech population
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F14%3A00080151" target="_blank" >RIV/00216224:14310/14:00080151 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The possible relationship between PAX9 gene polymorphisms and tooth agenesis in the Czech population
Original language description
Tooth agenesis is the most prevalent craniofacial congenital malformation in humans. Under the term tooth agenesis we understand absence of one or more teeth in the dentition. Up to 25 % of the population may lose at least one third molar. Agenesis of other permanent teeth, excluding third molars, ranges from 1,6 to 9,6 %, depending on the population studied. Primary dentition may also be affected, but with lower prevalence (from 0,5 to 0,9 %). This disorder can have a variety of causes ? from the influence of local causes during the formation of tooth germs primarily to the influence of genetic factors. Odontogenesis is very complicated and complex process involving over 300 so far identified that mediate interplay between cells of dental epithelium and adjacent mesenchyme. These molecules interact each other and create a complex system of regulatory linkages which monitors and controls the entire process of odontogenesis.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NT11420" target="_blank" >NT11420: Molecular diagnostics of hypodontia and possibilities of tooth autotransplantation</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů