Insect immunity after invasion of entomopathogenic nematodes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00080483" target="_blank" >RIV/00216224:14310/15:00080483 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Insect immunity after invasion of entomopathogenic nematodes
Original language description
Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/QJ1210047" target="_blank" >QJ1210047: Research and development of novel agents for honey bee health improvement</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů