An experimentally refined tool to assess the risks of the human dermal exposure to herbicide chlorotoluron
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00081592" target="_blank" >RIV/00216224:14310/15:00081592 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs11356-015-4252-x" target="_blank" >http://link.springer.com/article/10.1007%2Fs11356-015-4252-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11356-015-4252-x" target="_blank" >10.1007/s11356-015-4252-x</a>
Alternative languages
Result language
angličtina
Original language name
An experimentally refined tool to assess the risks of the human dermal exposure to herbicide chlorotoluron
Original language description
Dermal absorption of the herbicide chlorotoluron was measured using ex vivo pig skin in Franz diffusion cells in an automated system. The steady-state flux was calculated, as well as the permeability coefficient, which is 0.0038 cm h(-1). The permeability coefficient (K-p) is a key factor when predicting human health risks resulting from dermal exposition to a substance. The experimental determination of this parameter filled data gaps regarding the dermal absorption of chlorotoluron. The experimental permeability coefficient was subsequently used to calculate the dermal absorbed dose during some exposure scenarios. Reference doses were revised, and screening risk assessment process was done to calculate the risks resulting from exposure to chlorotoluron. This refined new approach proved to be a useful tool for human health risk assessment in the areas with these herbicide applications.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DN - Environmental impact on health
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Environmental Science and Pollution Research
ISSN
0944-1344
e-ISSN
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Volume of the periodical
22
Issue of the periodical within the volume
14
Country of publishing house
DE - GERMANY
Number of pages
8
Pages from-to
10713-10720
UT code for WoS article
000357344300033
EID of the result in the Scopus database
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