Altered intensity coding in the salicylate-overdose animal model of tinnitus
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F15%3A00083312" target="_blank" >RIV/00216224:14310/15:00083312 - isvavai.cz</a>
Alternative codes found
RIV/67985823:_____/15:00452139
Result on the web
<a href="http://dx.doi.org/10.1016/j.biosystems.2015.06.010" target="_blank" >http://dx.doi.org/10.1016/j.biosystems.2015.06.010</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.biosystems.2015.06.010" target="_blank" >10.1016/j.biosystems.2015.06.010</a>
Alternative languages
Result language
angličtina
Original language name
Altered intensity coding in the salicylate-overdose animal model of tinnitus
Original language description
Tinnitus is one of the leading disorders of hearing with no effective cure as its pathophysiological mechanisms remain unclear. While the sensitivity to sound is well-known to be affected, exactly how intensity coding per se is altered remains unclear. To address this issue, we used a salicylate-overdose animal model of tinnitus to measure auditory cortical evoked potentials at various stimulus levels, and analyzed on single-trial basis the response strength and its variance for the computation of the lower bound of Fisher information. Based on Fisher information profiles, we compared the precision or efficiency of intensity coding before and after salicylate-treatment. We found that after salicylate treatment, intensity coding was unexpectedly improved, rather than impaired. Also, the improvement varied in a sound-dependent way.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BA - General mathematics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA15-08066S" target="_blank" >GA15-08066S: Efficiency of information transfer and the role of energetic constraints in neuronal systems</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BioSystems
ISSN
0303-2647
e-ISSN
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Volume of the periodical
136
Issue of the periodical within the volume
october
Country of publishing house
GB - UNITED KINGDOM
Number of pages
7
Pages from-to
113-119
UT code for WoS article
000366535200014
EID of the result in the Scopus database
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