CenH3 evolution reflects meiotic symmetry as predicted by the centromere drive model
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00088363" target="_blank" >RIV/00216224:14310/16:00088363 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1038/srep33308" target="_blank" >http://dx.doi.org/10.1038/srep33308</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/srep33308" target="_blank" >10.1038/srep33308</a>
Alternative languages
Result language
angličtina
Original language name
CenH3 evolution reflects meiotic symmetry as predicted by the centromere drive model
Original language description
The centromere drive model explaining rapid evolution of eukaryotic centromeres predicts higher frequency of positive selection acting on centromeric histone H3 (CenH3) in clades with asymmetric meiosis compared to the clades with only symmetric meiosis. However, despite the impression one might get from the literature, this key prediction of the centromere drive model has not only never been confirmed, but it has never been tested, because all the previous studies dealt only with the presence or absence instead of the frequency of positive selection. To provide evidence for or against different frequencies of positively selected CenH3 in asymmetrics and symmetrics, we have inferred the selective pressures acting on CenH3 in seventeen eukaryotic clades, including plants, animals, fungi, ciliates and apicomplexa, using codon-substitution models, and compared the inferred frequencies between asymmetrics and symmetrics in a quantitative manner.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EF - Botany
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA13-29362S" target="_blank" >GA13-29362S: Evolution of holocentric chromosomes</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Scientific Reports
ISSN
2045-2322
e-ISSN
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Volume of the periodical
6
Issue of the periodical within the volume
September
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
"nestrankovano"
UT code for WoS article
000383188000001
EID of the result in the Scopus database
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