Characterization of total retinoid-like activity of compounds produced by three common phytoplankton species

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00088800" target="_blank" >RIV/00216224:14310/16:00088800 - isvavai.cz</a>
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S156898831630021X" target="_blank" >http://www.sciencedirect.com/science/article/pii/S156898831630021X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.hal.2016.11.002" target="_blank" >10.1016/j.hal.2016.11.002</a>

Result language
angličtina
Original language name
Characterization of total retinoid-like activity of compounds produced by three common phytoplankton species
Original language description
Phytoplankton can produce various bioactive metabolites, which may affect other organisms in the aquatic environment. This study provides the first information on the total retinoid-like activity associated with both intracellular and extracellular metabolites produced by selected phytoplankton species that could play a role in teratogenic effects and developmental disruption in exposed organisms. The studied species included a coccoid cyanobacteria, a filamentous cyanobacteria and a green alga, all of which commonly occur in freshwater bodies in Europe. Methanolic extracts from cellular material and extracellular exudates were prepared from cultures cultivated in two light-intensity variants with five replicates for each species. The retinoid-like activity was evaluated by in vitro assays along with chemical analyses of two potent retinoic acids (all-trans retinoic acid (ATRA) and 9cis-RA).
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
DA - Hydrology and limnology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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