A new approach to pretreatment of a pencil graphite electrode surface for 3N-methyladenine determination

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00090229" target="_blank" >RIV/00216224:14310/16:00090229 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
A new approach to pretreatment of a pencil graphite electrode surface for 3N-methyladenine determination
Original language description
Purine derivatives are important molecules in human metabolism. DNA is constantly attacked by many species forming different products such as oxidized forms. Methyl groups have been commonly observed in the case of DNA damage. The purine ring of adenine can be methylated at different positions. So far there have been only few studies of electrochemical behavior aimed at oxidation processes of N-methyladenines. We found out the possibility of measuring 3N-methyladenine (3N-mAde) on a pencil graphite electrode (PeGE) whose surface requires a surface pretreatment. The unique surface morphology of the PeGE, together with adsorption stripping, gives us the opportunity to study 3N-mAde signals. It is noteworthy that there were no 3N-mAde signals at a glassy carbon (GC) electrode at the same experimental conditions.
Czech name
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Czech description
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Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
XVI. Workshop of Physical Chemists and Electrochemists
ISBN
9788021082670
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
149-153
Publisher name
Masarykova univerzita
Place of publication
Brno
Event location
Brno
Event date
Jun 6, 2016
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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