STUDYING OF COMPETITIVE INTERACTIONS OF DRUGS WITH HUMAN SERUM ALBUMIN BY CAPILLARY ELECTROPHORESIS-FRONTAL ANALYSIS
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F16%3A00092190" target="_blank" >RIV/00216224:14310/16:00092190 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
STUDYING OF COMPETITIVE INTERACTIONS OF DRUGS WITH HUMAN SERUM ALBUMIN BY CAPILLARY ELECTROPHORESIS-FRONTAL ANALYSIS
Original language description
Drug-protein interactions have a significant effect on pharmacodynamics and pharmacokinetics properties of drugs. Bound fraction of drugs is reservoir, whereas free fraction provides pharmacological effect.Study of drug-protein interactions is thus important in the clinical therapy and in the development of new drugs.In this study displacement of L tryptophan from its binding site on human serum albumin (HSA) by several drugs was investigated by capillary electrophoresis frontal analysis (CE-FA).
Czech name
—
Czech description
—
Classification
Type
D - Article in proceedings
CEP classification
CE - Biochemistry
OECD FORD branch
—
Result continuities
Project
—
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
13 th International Interdisciplinary Meeting on Bioanalysis CECE 2016
ISBN
9788090495944
ISSN
—
e-ISSN
—
Number of pages
4
Pages from-to
202-205
Publisher name
Institute of Analytical Chemistry of the CAS, v. v. i., Brno, Czech Republic
Place of publication
Brno, Czech Republic
Event location
Brno, Czech Republic
Event date
Jan 1, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
—