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Optimization of media cultivation for intestinal sulfate-reducing bacteria

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00097798" target="_blank" >RIV/00216224:14310/17:00097798 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Optimization of media cultivation for intestinal sulfate-reducing bacteria

  • Original language description

    Intestinal sulfate-reducing bacteria (SRB) are anaerobic microorganisms which make part of animal and human large intestine microbiota. Hydrogen sulfide is a final product of SRB metabolism. Its production in the high concentration has negative impact on epithelial cells of the large bowel. This toxic compound can be involved in intestinal inflammation and affects gastrointestinal motility, secretion and nociception, and leads to diseases like an ulcerative colitis, Crohn's disease or even cancer. Isolation of SRB from the mixture of human and animals’ microbiota and their cultivation is also difficult. Some species of SRB such as Bilophila wadsworthia and Lawsoni intracellularis are uncultured. Other genera of the Desulfovibrionaceae family also grow poorly in cultivation medium or are uncultured.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    10600 - Biological sciences

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů