Optimization of media cultivation for intestinal sulfate-reducing bacteria
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F17%3A00097798" target="_blank" >RIV/00216224:14310/17:00097798 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Optimization of media cultivation for intestinal sulfate-reducing bacteria
Original language description
Intestinal sulfate-reducing bacteria (SRB) are anaerobic microorganisms which make part of animal and human large intestine microbiota. Hydrogen sulfide is a final product of SRB metabolism. Its production in the high concentration has negative impact on epithelial cells of the large bowel. This toxic compound can be involved in intestinal inflammation and affects gastrointestinal motility, secretion and nociception, and leads to diseases like an ulcerative colitis, Crohn's disease or even cancer. Isolation of SRB from the mixture of human and animals’ microbiota and their cultivation is also difficult. Some species of SRB such as Bilophila wadsworthia and Lawsoni intracellularis are uncultured. Other genera of the Desulfovibrionaceae family also grow poorly in cultivation medium or are uncultured.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10600 - Biological sciences
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů