Metagenomic research of the ancient human dental calculus as a potential source for the study of rare infectious diseases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F22%3A00125840" target="_blank" >RIV/00216224:14310/22:00125840 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Metagenomic research of the ancient human dental calculus as a potential source for the study of rare infectious diseases
Original language description
Ancient human dental calculus has been intensively studied in recent years by diverse molecular methods. It was found to be a rich and important source for detailed study of past populations, as well as their pathogens. This study presents the results of metagenomic research by sequencing 16S rRNA gene from bacteria trapped inside tartar and suggests the possibility of using such an approach to screen samples for rare infectious diseases. Dental calculus samples came from populations of four different periods: Copper Age (Funnelbeaker culture), Bronze Age (Unetice), Middle Ages (Great Moravia), and early modern period, which provides a comparison. Genera found include Nocardia, Haemophilus, Bartonella, Shigella, or Neisseria. Applied approach is recommended as a robust screening method. All laboratory procedures were carried out in a dedicated ancient biomolecule facility of the Laboratory of Biological and Molecular Anthropology.
Czech name
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Czech description
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Project
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Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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