Detection of Single Ag Nanoparticles Using Laser Desorption/Ionization Mass Spectrometry

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F23%3A00131251" target="_blank" >RIV/00216224:14310/23:00131251 - isvavai.cz</a>
Result on the web
<a href="https://pubs.acs.org/doi/10.1021/jasms.3c00137" target="_blank" >https://pubs.acs.org/doi/10.1021/jasms.3c00137</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/jasms.3c00137" target="_blank" >10.1021/jasms.3c00137</a>

Result language
angličtina
Original language name
Detection of Single Ag Nanoparticles Using Laser Desorption/Ionization Mass Spectrometry
Original language description
The detection of a single entity (molecule, cell, particle, etc.) was always a challenging subject. Here we demonstrate the detection of single Ag nanoparticles (NPs) using subatmospheric pressure laser desorption/ionization mass spectrometry (LDI MS). The sample preparation, measurement conditions, generated ions, and limiting experimental factors are discussed here. We detected from 84 to 95% of the deposited 80 nm Ag NPs. The presented LDI MS platform is an alternative to laser ablation inductively coupled plasma mass spectrometry for imaging distribution of individual NPs across the sample surface and has a great potential for multiplexed mapping of low-abundance biomarkers in tissues.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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