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Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F23%3A00132316" target="_blank" >RIV/00216224:14310/23:00132316 - isvavai.cz</a>

  • Result on the web

    <a href="https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01111" target="_blank" >https://pubs.acs.org/doi/10.1021/acs.jchemed.2c01111</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acs.jchemed.2c01111" target="_blank" >10.1021/acs.jchemed.2c01111</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Laser Ablation Inductively Coupled Plasma Mass Spectrometry as a Powerful Tool for Spatially Resolved Analysis: An Experiment for Undergraduate Analytical Chemistry Laboratory

  • Original language description

    A new experiment using laser ablation with inductively coupled plasma mass spectrometry (LA-ICP-MS) was designed for chemistry undergraduate students. While most analytical methods only provide information on the amount of the analyte, LA-ICP-MS allows extra information on the distribution of the element in the sample. Because it achieves excellent limits of detection (sub mu g center dot g-1) and high spatial resolution (micrometer scale), it is a powerful technique for imaging any sample. A thin section of mouse tissue was used as a model sample to demonstrate these abilities. The student's task was to determine the distribution of the essential elements Zn, Cu, and Pt (Pt introduced into the tumor tissue from the cytostatic drug (cis Pt)) and quantify their amount.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30104 - Pharmacology and pharmacy

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Chemical Education

  • ISSN

    0021-9584

  • e-ISSN

    1938-1328

  • Volume of the periodical

    100

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    7

  • Pages from-to

    1973-1979

  • UT code for WoS article

    000979469700001

  • EID of the result in the Scopus database

    2-s2.0-85154050330