Nanostructured cobalt(II) phthalocyanine modified screen-printed electrodes for the determination of thiocyanate in human saliva
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F24%3A00136105" target="_blank" >RIV/00216224:14310/24:00136105 - isvavai.cz</a>
Result on the web
<a href="https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/elan.202400011" target="_blank" >https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/elan.202400011</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elan.202400011" target="_blank" >10.1002/elan.202400011</a>
Alternative languages
Result language
angličtina
Original language name
Nanostructured cobalt(II) phthalocyanine modified screen-printed electrodes for the determination of thiocyanate in human saliva
Original language description
Salivary thiocyanate is a biomarker of individual health that notably allows for the discrimination between smokers and non-smokers. Recent studies have also demonstrated its potential as a biomarker of cystic fibrosis, thus rendering the development of methods for its determination in saliva of immense importance. In response, we report on the development of graphite screen-printed electrodes (SPE) modified with cobalt(II) phthalocyanine nanosticks (CoPcNst), as low-cost and semi-disposable sensors for the determination of thiocyanate ion (SCN−) in human saliva. CoPCNst were synthesized and characterized using scanning electron microscopy, x-ray diffraction, as well as infrared and Raman spectroscopies. The results revealed a structural proximity to the recently identified J-polymorph. Compared with the electrode modified with commercial, beta-structure cobalt(II) phthalocyanine, the CoPc Nst/SPE provided four times better LOD and LOQ (0.49 and 1.62 μM) for thiocyanate determination by differential pulse voltammetry. The response was linear up to 20 μM SCN− (R2=0.996) and it was not affected by excess of common electro active compounds, such as ascorbic and uric acid. The analytical utility of CoPc Nst/SPE in human saliva is demonstrated.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electroanalysis
ISSN
1040-0397
e-ISSN
1521-4109
Volume of the periodical
36
Issue of the periodical within the volume
10
Country of publishing house
DE - GERMANY
Number of pages
10
Pages from-to
1-10
UT code for WoS article
001235737500001
EID of the result in the Scopus database
2-s2.0-85194551599