Vitamin B12 intake during pregnancy linked to child speech development and intelligence quotient
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F25%3A00140431" target="_blank" >RIV/00216224:14310/25:00140431 - isvavai.cz</a>
Result on the web
<a href="https://academic.oup.com/jpubhealth/advance-article/doi/10.1093/pubmed/fdae307/7923983" target="_blank" >https://academic.oup.com/jpubhealth/advance-article/doi/10.1093/pubmed/fdae307/7923983</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/pubmed/fdae307" target="_blank" >10.1093/pubmed/fdae307</a>
Alternative languages
Result language
angličtina
Original language name
Vitamin B12 intake during pregnancy linked to child speech development and intelligence quotient
Original language description
Background Nutrient deficiencies during pregnancy may affect offspring development. We aim to examine the association between prenatal vitamin B12 intake and children’s cognitive development. Methods A total of 5151 mother–child pairs from the Czech part of ELSPAC study were included in the analysis. Dietary information was obtained during pregnancy using food frequency questionnaire. Parents reported on their child’s speech and language development at 18 months, 3, 5 and 7 years. Intelligence quotient (IQ) was measured at 8 years in subcohort of 854 children. Results Children of mothers with higher vitamin B12 intake demonstrated higher scores in language (B = 0.20, 95% CI 0.06, 0.34) and talking and understanding (B = 2.39, 95% CI 0.97, 3.80) in a fully adjusted model at 18 months. Additionally, they were more likely to get maximum points in the intelligibility test at age 3 (OR = 1.05, 95% CI 1.01, 1.09) in unadjusted model, however, not in fully adjusted model. We found a positive effect of higher vitamin B12 intake on verbal IQ (B = 1.08, 95% CI 0.09, 2.08). Conclusions We identified consistent associations between prenatal vitamin B12 intake and children’s cognitive development. The results suggest that inadequate vitamin B12 during pregnancy may negatively affect children’s cognitive development, particularly in speech and language.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
<a href="/en/project/LX22NPO5101" target="_blank" >LX22NPO5101: The National Institute for Research on the Socioeconomic Impact of Diseases and Systemic Risks</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF PUBLIC HEALTH
ISSN
1741-3842
e-ISSN
1741-3850
Volume of the periodical
47
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
11
Pages from-to
34-44
UT code for WoS article
001377198500001
EID of the result in the Scopus database
2-s2.0-86000143403