Comparison of pharmacodynamic and pharmacokinetic aspects in systemic and local infection during phage therapy in a murine model

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F25%3A00143293" target="_blank" >RIV/00216224:14310/25:00143293 - isvavai.cz</a>
Result on the web
—
DOI - Digital Object Identifier
—

Result language
angličtina
Original language name
Comparison of pharmacodynamic and pharmacokinetic aspects in systemic and local infection during phage therapy in a murine model
Original language description
Although the use of bacteriophages to treat bacterial infections has a long history, and the growing international crisis of resistance to standard antibiotics encourages alternative treatment approaches, phage therapy is not currently used as a standard medical approach. One explanation for why phage therapy has not been widely adopted in clinical practice is that pharmacological data on preclinical and clinical testing of phages are still lacking. Our study compares the pharmacological aspects of phage therapy in a murine model of open wound, where systemic infection occurs, and in a murine model of abscess, which simulates local infection.
Czech name
—
Czech description
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)