The hypothyroid state restricts the conversion of regenerating soleus muscle grafted into fast EDL muscle

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F98%3A00001199" target="_blank" >RIV/00216224:14310/98:00001199 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The hypothyroid state restricts the conversion of regenerating soleus muscle grafted into fast EDL muscle

Original language description

Soleus (SOL) muscles of 21- to 28-day-old inbred rats of the Lewis strain were grafted into the fast extensor digitorum longus (EDL) muscles in young adult euthyroid, hyperthyroid or hypothyroid inbred rats of the same strain. One to 3 months after the operation, rats were killed and muscle histochemical profiles and expression of myosin heavy chain (MyHC) isoforms were determined. It can be concluded that normal levels of thyroid hormones are required for the expression of the fast MyHC isoforms in theregenerating SOL muscle reinnervated by the fast EDL nerve.

Czech name

The hypothyroid state restricts the conversion of regenerating soleus muscle grafted into fast EDL muscle

Czech description

Soleus (SOL) muscles of 21- to 28-day-old inbred rats of the Lewis strain were grafted into the fast extensor digitorum longus (EDL) muscles in young adult euthyroid, hyperthyroid or hypothyroid inbred rats of the same strain. One to 3 months after the operation, rats were killed and muscle histochemical profiles and expression of myosin heavy chain (MyHC) isoforms were determined. It can be concluded that normal levels of thyroid hormones are required for the expression of the fast MyHC isoforms in theregenerating SOL muscle reinnervated by the fast EDL nerve.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EA - Morphology and cytology

OECD FORD branch

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Project

<a href="/en/project/GA304%2F97%2F0516" target="_blank" >GA304/97/0516: Analysis of the role of myogenic and neurogenic factors regulating the expression of specific phenotypes in intrafusal muscle fibres.</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

1998

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Physiology (London) [IF=4.727 (1997); SCI #cit.<1>]

ISSN

0022-3751

e-ISSN

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Volume of the periodical

511.P

Issue of the periodical within the volume

6,

Country of publishing house

GB - UNITED KINGDOM

Number of pages

1

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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