Exchange aberrations among 11 chromosomes of human lymphocytes induced by gamma-rays

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F01%3A00004206" target="_blank" >RIV/00216224:14330/01:00004206 - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/01:17013008

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Exchange aberrations among 11 chromosomes of human lymphocytes induced by gamma-rays

Original language description

Purpose: To detect the frequencies of inter-changes among 11 chromosomes in lymphocytes irradiated with gamma -rays and to find out whether these frequencies reflect the proximity of some of these chromosomes within the interphase nucleus. Material and methods: Exchange aberrations were detected in the first mitosis after irradiation of human lymphocytes with 3 and 5 Gy gamma -rays of` Co-60. Two-colour repeated FISH with two differently chemically modified probes in each hybridization was applied. Themicroscope stage positions of each mitosis were recorded after the first hybridization and used for the automatic scanning of images after all successive experiments. Five images were obtained for each mitosis differing in visualized pairs of chromosomes. Comparing these images, exchanges among 10 chromosomes could be detected. Painting of the p arm of chromosome 21 with the painting probe for chromosome 22 also made it possible to detect exchanges of this chromosome with other chromosom

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2001

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Radiation Biology

ISSN

0955-3002

e-ISSN

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Volume of the periodical

77

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

11

Pages from-to

419

UT code for WoS article

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EID of the result in the Scopus database

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