Study of the gene expression in malignant diseases by cDNA microarray technology

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F03%3A00009005" target="_blank" >RIV/00216224:14330/03:00009005 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14330/03:00008566
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Study of the gene expression in malignant diseases by cDNA microarray technology
Original language description
At the present time, a number of various diseases increases and thereby also increases the necessity of new therapeutic methods and new approaches to research. In last decade, many new technologies have been evolving, among others the technology called cDNA microarrays. This technology enables the detection of global gene-expression profiles, the identification of new molecular cancer markers. It makes possible the comparison of gene-expression profiles of various cancer tumors and cell lines under different environmental stress conditions. cDNA microarrays consist of hundreds or thousands spots with different cDNA sequences (resp. oligonucleotide sequence strands) organized in grids and they can contain more than 20,000 specific sequences on a singleslide. This technology is based on process of hybridization between immobilized cDNAs (oligonucleotides sequences) and reverse-transcribed cDNA from sample of total RNA. We used cDNA microarray technology to study gene expression profiles
Czech name
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Czech description
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Project
<a href="/en/project/NC6987" target="_blank" >NC6987: Epigenetic control of gene expression in malignant diseases</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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