Digital phantoms of cell nuclei and the use of simulations in nuclear studies

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F10%3A00045347" target="_blank" >RIV/00216224:14330/10:00045347 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Digital phantoms of cell nuclei and the use of simulations in nuclear studies
Original language description
Nuclear studies still face the problem of the quality of related image analysis results. Degradations caused by cell preparation, optics and electronics considerably affect most 2D and 3D image data acquired using fluorescence microscopy. That is why image processing algorithms applied to these data typically offer imprecise and unreliable results. As the ground truth (correct result) for given image data is not available in most experiments, the outputs of different image analysis methods can be neither verified nor compared to each other. Estimates of ground truth by experts are very subjective and strongly vary between different experts. In order to overcome these difficulties, we have created a toolbox [1] that can generate 3D digital phantoms of cell nuclei along with their corresponding images degraded by specific optics and electronics. The user can then apply image analysis methods to such simulated image data.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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