Uneven distribution of potential triplex sequences in the human genome. In silico study using the R/Bioconductor package triplex.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F14%3A00074890" target="_blank" >RIV/00216224:14330/14:00074890 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26230/14:PU111943
Result on the web
<a href="http://dx.doi.org/10.5220/0004824100800088" target="_blank" >http://dx.doi.org/10.5220/0004824100800088</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5220/0004824100800088" target="_blank" >10.5220/0004824100800088</a>

Result language
angličtina
Original language name
Uneven distribution of potential triplex sequences in the human genome. In silico study using the R/Bioconductor package triplex.
Original language description
Eukaryotic genomes are rich in sequences capable of forming non-B DNA structures. These structures are expected to play important roles in natural regulatory processes at levels above those of individual genes, such as whole genome dynamics or chromatinorganization, as well as in processes leading to the loss of these functions, such as cancer development. Recently, a number of authors have mapped the occurrence of potential quadruplex sequences in the human genome and found them to be associated withpromoters. In this paper, we set out to map the distribution and characteristics of potential triplex-forming sequences in human genome DNA sequences. Using the R/Bioconductor package {it triplex}, we found these sequences to be excluded from exons, while present mostly in a small number of repetitive sequence classes, especially short sequence tandem repeats (microsatellites), Alu and combined elements, such as SVA.
Czech name
—
Czech description
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms
ISBN
9789897580123
ISSN
—
e-ISSN
—
Number of pages
9
Pages from-to
80-88
Publisher name
SciTePress
Place of publication
Angers, France
Event location
Angers, FR
Event date
Mar 3, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
—

Similar results(10)