Unfolding and Interactive Exploration of Protein Tunnels and their Dynamics.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F16%3A00090614" target="_blank" >RIV/00216224:14330/16:00090614 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.2312/vcbm.20161265" target="_blank" >http://dx.doi.org/10.2312/vcbm.20161265</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2312/vcbm.20161265" target="_blank" >10.2312/vcbm.20161265</a>
Alternative languages
Result language
angličtina
Original language name
Unfolding and Interactive Exploration of Protein Tunnels and their Dynamics.
Original language description
The presence of tunnels in protein structures substantially influences their reactivity with other molecules. Therefore, studying their properties and changes over time has been in the scope of biochemists for decades. In this paper we introduce a novel approach for the comparative visualization and exploration of ensembles of tunnels. Our goal is to overcome occlusion problems with traditional tunnel representations while providing users a quick way to navigate through the input dataset and to identify potentially interesting tunnels. First, we unfold the input tunnels to a 2D representation enabling to observe the mutual position of amino acids forming the tunnel surface and the amount of surface they influence. These 2D images are subsequently described by image moments commonly used in image processing. This way we are able to detect similarities and outliers in the dataset, which are visualized as clusters in a scatterplot graph.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
IN - Informatics
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
EG VCBM 2016 Eurographics Workshop on Visual Computing for Biology and Medicine
ISBN
9783038680109
ISSN
2070-5786
e-ISSN
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Number of pages
10
Pages from-to
0-0
Publisher name
The Eurographics Association
Place of publication
Bergen
Event location
Bergen, Norway
Event date
Jan 1, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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