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Toward Robust Fully 3D Filopodium Segmentation and Tracking in Time-Lapse Fluorescence Microscopy

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F19%3A00107396" target="_blank" >RIV/00216224:14330/19:00107396 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1109/ICIP.2019.8803721" target="_blank" >http://dx.doi.org/10.1109/ICIP.2019.8803721</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1109/ICIP.2019.8803721" target="_blank" >10.1109/ICIP.2019.8803721</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Toward Robust Fully 3D Filopodium Segmentation and Tracking in Time-Lapse Fluorescence Microscopy

  • Original language description

    Development, parameter tuning, and objective benchmarking of bioimage analysis workflows heavily rely on the availability of diverse bioimage datasets accompanied by reference annotations. In this paper, we present a new benchmark dataset, FiloData3D, designed for in-depth performance assessments of fully 3D filopodium segmentation and tracking algorithms that emerged recently in the field. It consists of 180 synthetic, fully annotated, 3D time-lapse sequences of single lung cancer cells, combining different cell shapes, signal-to-noise ratios, and anisotropy ratios, which are the well-known factors that influence the quality of segmentation and tracking results. Using FiloData3D, we show that the number of filopodia and their lengths extracted are significantly underestimated in the case of traditional 2D protocols that prevail in daily practice compared to fully 3D measurements, calling for a procedural change in filopodial analyses of 3D+t bioimage data.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    26th IEEE International Conference on Image Processing

  • ISBN

    9781538662496

  • ISSN

    1522-4880

  • e-ISSN

  • Number of pages

    5

  • Pages from-to

    819-823

  • Publisher name

    IEEE

  • Place of publication

    Taipei

  • Event location

    Taipei, Taiwan

  • Event date

    Jan 1, 2019

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000521828600163