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Parameter Synthesis and Robustness Analysis of Rule-Based Models

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F20%3A00114280" target="_blank" >RIV/00216224:14330/20:00114280 - isvavai.cz</a>

  • Result on the web

    <a href="https://link.springer.com/chapter/10.1007/978-3-030-55754-6_3" target="_blank" >https://link.springer.com/chapter/10.1007/978-3-030-55754-6_3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/978-3-030-55754-6_3" target="_blank" >10.1007/978-3-030-55754-6_3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Parameter Synthesis and Robustness Analysis of Rule-Based Models

  • Original language description

    We introduce the Quantitative Biochemical Space Language, a rule-based language for a compact modelling of probabilistic behaviour of complex parameter-dependent biological systems. Application of rules is governed by an associated parametrised rate function, expressing partially known information about the behaviour of the modelled system. The parameter values influence the behaviour of the model. We propose a formal verification-based method for the synthesis of parameter values (parameter synthesis) which ensure the behaviour of the modelled system satisfies a given PCTL property. In addition, we demonstrate how this method can be used for robustness analysis.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Result continuities

  • Project

    <a href="/en/project/GA18-00178S" target="_blank" >GA18-00178S: Discrete Bifurcation Analysis of Reactive Systems</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    12th International Symposium on NASA Formal Methods, NFM 2020

  • ISBN

    9783030557539

  • ISSN

    0302-9743

  • e-ISSN

    1611-3349

  • Number of pages

    19

  • Pages from-to

    41-59

  • Publisher name

    Springer

  • Place of publication

    Moffett Field, CA, USA

  • Event location

    Neuveden

  • Event date

    Jan 1, 2020

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000890074700003