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Scalable Counting of Minimal Trap Spaces and Fixed Points in Boolean Networks

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F25%3A00143666" target="_blank" >RIV/00216224:14330/25:00143666 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.4230/LIPIcs.CP.2025.17" target="_blank" >http://dx.doi.org/10.4230/LIPIcs.CP.2025.17</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.4230/LIPIcs.CP.2025.17" target="_blank" >10.4230/LIPIcs.CP.2025.17</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Scalable Counting of Minimal Trap Spaces and Fixed Points in Boolean Networks

  • Original language description

    Boolean Networks (BNs) serve as a fundamental modeling framework for capturing complex dynamical systems across various domains, including systems biology, computational logic, and artificial intelligence. A crucial property of BNs is the presence of trap spaces - subspaces of the state space that, once entered, cannot be exited. Minimal trap spaces, in particular, play a significant role in analyzing the long-term behavior of BNs, making their efficient enumeration and counting essential. The fixed points in BNs are a special case of minimal trap spaces. In this work, we formulate several meaningful counting problems related to minimal trap spaces and fixed points in BNs. These problems provide valuable insights both within BN theory (e.g., in probabilistic reasoning and dynamical analysis) and in broader application areas, including systems biology, abstract argumentation, and logic programming. To address these computational challenges, we propose novel methods based on approximate answer set counting, leveraging techniques from answer set programming. Our approach efficiently approximates the number of minimal trap spaces and the number of fixed points without requiring exhaustive enumeration, making it particularly well-suited for large-scale BNs. Our experimental evaluation on an extensive and diverse set of benchmark instances shows that our methods significantly improve the feasibility of counting minimal trap spaces and fixed points, paving the way for new applications in BN analysis and beyond.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    31ST INTERNATIONAL CONFERENCE ON PRINCIPLES AND PRACTICE OF CONSTRAINT PROGRAMMING, CP 2025

  • ISBN

    9783959773805

  • ISSN

    1868-8969

  • e-ISSN

  • Number of pages

    26

  • Pages from-to

    1-26

  • Publisher name

    SCHLOSS DAGSTUHL, LEIBNIZ CENTER INFORMATICS

  • Place of publication

    Dagstuhl, Germany

  • Event location

    GLASGOW, SCOTLAND

  • Event date

    Aug 10, 2025

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    001590355100017