Analysis of Biomolecules through Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Employing Nanomaterials

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F11%3A00050122" target="_blank" >RIV/00216224:14740/11:00050122 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1002/jccs.201190120" target="_blank" >http://dx.doi.org/10.1002/jccs.201190120</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jccs.201190120" target="_blank" >10.1002/jccs.201190120</a>

Result language

angličtina

Original language name

Analysis of Biomolecules through Surface-Assisted Laser Desorption/Ionization Mass Spectrometry Employing Nanomaterials

Original language description

Nanomaterials, primarily nanoparticles (NPs), can serve as an alternative matrix for the analysis of various biomolecules through SALDI MS. SALDI MS has been developed to overcome poor reproducibility and high background in the low mass region commonly occurring in MALDI MS. Various nanomaterials, unmodified or functionalized with recognition ligands, can have a strong affinity toward certain analytes and thus are applicable for their concentration and enrichment from complex biological matrices. In mass spectrometry imaging (MSI), the use of NPs instead of the conventional matrices can improve the spatial resolution up to the cellular level. In this review, the nature of NPs, the methods of sample preparation and approaches for quantitation of biomolecules through SALDI MS are discussed. Practical applications and limitations of SALDI MS employing NPs for separate samples and MSI are mentioned.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of the Chinese Chemical Society

ISSN

0009-4536

e-ISSN

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Volume of the periodical

58

Issue of the periodical within the volume

6

Country of publishing house

TW - TAIWAN (PROVINCE OF CHINA)

Number of pages

10

Pages from-to

769-778

UT code for WoS article

000296267600009

EID of the result in the Scopus database

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