The use of an internal standard extends the linear range of the SALDI MS analyses
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00057868" target="_blank" >RIV/00216224:14740/12:00057868 - isvavai.cz</a>
Result on the web
<a href="http://www.ce-ce.org/cece2012/Proceedings%20CECE%202012%20Final+late%20abstracts_web.pdf" target="_blank" >http://www.ce-ce.org/cece2012/Proceedings%20CECE%202012%20Final+late%20abstracts_web.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
The use of an internal standard extends the linear range of the SALDI MS analyses
Original language description
Surface-assisted laser desorption/ionization mass spectrometry (SALDI MS) employing gold nanoparticles (Au NPs) has been presented as a useful method for the both qualitative and quantitative analysis of low molecular weight analytes. Besides the well-known benefit, such as the improvement in the analysis precision, the use of an internal standard was observed to extend the linear range of SALDI MS. Without the use of the internal standard, the linear range is presumably limited by the saturation of theAu NP surface where the desorption process takes place: at higher analyte concentration, an imperfect, multilayer assembly is formed leading to inefficient desorption and/or ionization and thus to reduced linearity and poor reproducibility.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
CECE 2012
ISBN
9788090495913
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
317-320
Publisher name
9th International Interdisciplinary Meeting on Bioanalysis, CECE 2012
Place of publication
Brno
Event location
Brno
Event date
Jan 1, 2012
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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