Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00060270" target="_blank" >RIV/00216224:14740/12:00060270 - isvavai.cz</a>
Alternative codes found
RIV/00209805:_____/12:#0000336
Result on the web
<a href="http://www.wjgnet.com/1007-9327/full/v18/i22/2827.htm" target="_blank" >http://www.wjgnet.com/1007-9327/full/v18/i22/2827.htm</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3748/wjg.v18.i22.2827" target="_blank" >10.3748/wjg.v18.i22.2827</a>
Alternative languages
Result language
angličtina
Original language name
Evaluation of SNPs in miR-196-a2, miR-27a and miR-146a as risk factors of colorectal cancer
Original language description
In order to investigate the effect of selected single nucleotide polymorphisms (SNPs) in miR-196a2, miR-27a and miR-146a genes in CRC, we performed a case-control study of 197 cases of sporadic CRC and 212 cancer-free controls originating from the Central-European Caucasian population using TaqMan Real-Time polymerase chain reaction and allelic discrimination analysis.The genotype and allele frequencies of SNPs were compared between the cases and the controls. Unfortunately, none of the performed analysis showed any statistically significant results. Our data suggest a lack of association between rs11614913, rs895819 and rs2910164 and colorectal cancer risk in the Central-European Caucasian population, a population with an extremely high incidence of sporadic colorectal cancer.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
World Journal of Gastroenterology
ISSN
1007-9327
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
22
Country of publishing house
CN - CHINA
Number of pages
5
Pages from-to
2827-2831
UT code for WoS article
000305445200012
EID of the result in the Scopus database
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