Could piracetam potentiate behavioural effects of psychostimulants?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F12%3A00060456" target="_blank" >RIV/00216224:14740/12:00060456 - isvavai.cz</a>

Alternative codes found

RIV/62157124:16170/12:43870991

Result on the web

<a href="http://www.ncbi.nlm.nih.gov/pubmed/22607774" target="_blank" >http://www.ncbi.nlm.nih.gov/pubmed/22607774</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mehy.2012.04.041" target="_blank" >10.1016/j.mehy.2012.04.041</a>

Result language

angličtina

Original language name

Could piracetam potentiate behavioural effects of psychostimulants?

Original language description

Press and internet reports mention abuse of nootropic drug piracetam (PIR) in combination with psychostimulants methamphetamine (MET) or 4-methylenedioxymethamphetamine (MDMA). These combinations are believed to produce more profound desirable effects, while decreasing hangover. However, there is a lack of valid experimental studies on such drug-drug interactions in the scientific literature available. Our hypothesis proposes that a functional interaction exists between PIR and amphetamine psychostimulants (MET and MDMA) which can potentiate psychostimulant behavioural effects. Our hypothesis is supported by the results of our pilot experiment testing acute effects of drugs given to mice intraperitoneally (Vehicle, n=12; MET 2.5mg/kg, n=10; MDMA 2.5mg/kg, n=11; PIR 300mg/kg, n=12; PIR+MET, n=12; PIR+MDMA, n=11) in the Open Field Test (Actitrack, Panlab, Spain).

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medical Hypotheses

ISSN

0306-9877

e-ISSN

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Volume of the periodical

79

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

3

Pages from-to

216-218

UT code for WoS article

000306770700025

EID of the result in the Scopus database

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