Protein engineering of beta-D-mannosidase

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F13%3A00066122" target="_blank" >RIV/00216224:14740/13:00066122 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Protein engineering of beta-D-mannosidase
Original language description
N-Acetyl-D-mannosamine (ManNAc) is often used as a precursor in the chemical or enzymatic synthesis of the neuraminic acids found in glycolipids and glycoproteins. ManNAc is also a synthetic intermediate for a number of carbohydrate-derived families of biologically active compounds and pharmaceutical candidates. For this reason ManNAc is of keen interest to scientists around the world. The main goal of this work, because no N-Acetyl-mannosaminidase has been identified in the nature, is to produce N-acetyl-mannosaminidase via mutagenesis of beta-D-mannosidase and to apply this new enzyme in possible enzymatic synthesis of structures containing ManNAc.
Czech name
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Czech description
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Project
<a href="/en/project/GAP207%2F10%2F0321" target="_blank" >GAP207/10/0321: The ways to N-acetyl-mannosamine structures via mannoside metabolizing enzymes</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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