DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F13%3A00070577" target="_blank" >RIV/00216224:14740/13:00070577 - isvavai.cz</a>

Result on the web

<a href="http://europepmc.org/abstract/MED/23474852" target="_blank" >http://europepmc.org/abstract/MED/23474852</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-013-0990-4" target="_blank" >10.1007/s00702-013-0990-4</a>

Result language

angličtina

Original language name

DBS amplitude setting can improve aspects of quality of life in patients with Parkinson's disease

Original language description

The DBS STN is a non-curative treatment; its effect on the patient's quality of life (QoL) determines the therapeutic success of this procedure. We aimed to assess whether stimulation parameters setting may influence also some of the non-motor aspects ofQoL. The QoL was assessed by PDQ-39 questionnaire. The questionnaire was administered to patients before and after the DBS surgery. A sham change of stimulation amplitude was performed before the actual increase. After the further amplitude increase insubgroup of patients (mean increase of amplitude of 0.35 V), there was a statistically significant additional improvement of total PDQ-39 score by another 22.9 %. In this group the emotions, stigma and communication subscales improved after the stimulation increase, without further change of UPDRS III.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

—

Project

<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

—

Volume of the periodical

120

Issue of the periodical within the volume

4

Country of publishing house

AT - AUSTRIA

Number of pages

6

Pages from-to

643-648

UT code for WoS article

000317076600022

EID of the result in the Scopus database

—