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Diode laser thermal vaporisation inductively coupled plasma mass spectrometry of cobalamins

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00073491" target="_blank" >RIV/00216224:14740/14:00073491 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Diode laser thermal vaporisation inductively coupled plasma mass spectrometry of cobalamins

  • Original language description

    A diode laser thermal vaporization (DLTV) is a sample introduction technique to inductively coupled plasma (ICP), which presents a low-cost alternative to the commercial laser-ablation systems and nebulizers The determination of cobalamin derivatives isof great importance in pharmaceutical analysis. Here we present determination of cobalamins using DLTV ICP MS. Furthermore, the coupling of sensitive DLTV ICP MS with the TLC separation is investigated. Ascending thin layer chromatography (TLC) separation of cobalamins was performed on cellulose ? aluminum sheets at ambient temperature in the dark, eluting with solution of n-butanol:ethanol:water (10:3:7). The black ink line was printed over the evolved chromatography sheet, which was used as the substrate for the DLTV technique. The TLC chromatogram was scanned in a simple laboratory-built chamber with the diode laser.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů