Compromised telomere maintenance in hypomethylated Arabidopsis thaliana plants
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00073694" target="_blank" >RIV/00216224:14740/14:00073694 - isvavai.cz</a>
Alternative codes found
RIV/68081707:_____/14:00427822 RIV/61388963:_____/14:00427822
Result on the web
<a href="http://nar.oxfordjournals.org/content/42/5/2919.long" target="_blank" >http://nar.oxfordjournals.org/content/42/5/2919.long</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/nar/gkt1285" target="_blank" >10.1093/nar/gkt1285</a>
Alternative languages
Result language
angličtina
Original language name
Compromised telomere maintenance in hypomethylated Arabidopsis thaliana plants
Original language description
Telomeres, nucleoprotein structures at the ends of linear eukaryotic chromosomes, are important for the maintenance of genomic stability. Telomeres were considered as typical heterochromatic regions, but in light of recent results, this view should be reconsidered. Asymmetrically located cytosines in plant telomeric DNA repeats may be substrates for a DNA methyltransferase enzyme and indeed, it was shown that these repeats are methylated. Here, we analyse the methylation of telomeric cytosines and the length of telomeres in Arabidopsis thaliana methylation mutants (met 1-3 and ddm 1-8), and in their wild-type siblings that were germinated in the presence of hypomethylation drugs. Our results show that cytosine methylation in telomeric repeats depends on the activity of MET1 and DDM1 enzymes.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nucleic Acids Research
ISSN
0305-1048
e-ISSN
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Volume of the periodical
42
Issue of the periodical within the volume
5
Country of publishing house
GB - UNITED KINGDOM
Number of pages
13
Pages from-to
2919-2931
UT code for WoS article
000333093600018
EID of the result in the Scopus database
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