Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F14%3A00074325" target="_blank" >RIV/00216224:14740/14:00074325 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs11910-014-0491-3" target="_blank" >http://link.springer.com/article/10.1007%2Fs11910-014-0491-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s11910-014-0491-3" target="_blank" >10.1007/s11910-014-0491-3</a>
Alternative languages
Result language
angličtina
Original language name
Disruption of Resting Functional Connectivity in Alzheimer's Patients and At-Risk Subjects
Original language description
The resting brain exhibits continuous intrinsic activity, which is correlated between groups of regions forming resting state networks. Evaluating resting connectivity is a popular approach for studying brain diseases. Several hundred studies are now available that address integrity of resting connectivity in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI), as well as preclinical at-risk subjects. Most studies focus on the default mode network, a system of specific brain areasshowing strong connected resting activity that attenuates during goal-directed behavior. The extent of intrinsic brain activity tends to be strongly correlated with cognitive processes and is specifically disrupted in AD and MCI patients and at-risk subjects, with changes seeming to evolve during the transition between the disease stages.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
ISSN
1528-4042
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
10
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
"nestránkované"
UT code for WoS article
000342073900008
EID of the result in the Scopus database
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