Auxin-binding pocket of ABP1 is crucial for its gain-of-function cellular and developmental roles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00081165" target="_blank" >RIV/00216224:14740/15:00081165 - isvavai.cz</a>
Alternative codes found
RIV/61389030:_____/15:00447356
Result on the web
<a href="http://jxb.oxfordjournals.org/content/66/16/5055.abstract" target="_blank" >http://jxb.oxfordjournals.org/content/66/16/5055.abstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/jxb/erv177" target="_blank" >10.1093/jxb/erv177</a>

Result language
angličtina
Original language name
Auxin-binding pocket of ABP1 is crucial for its gain-of-function cellular and developmental roles
Original language description
The plant hormone auxin is a key regulator of plant growth and development. Auxin levels are sensed and interpreted by distinct receptor systems that activate a broad range of cellular responses. The Auxin-Binding Protein1 (ABP1) that has been identifiedbased on its ability to bind auxin with high affinity is a prime candidate for the extracellular receptor responsible for mediating a range of auxin effects, in particular, the fast non-transcriptional ones. Contradictory genetic studies suggested prominent or no importance of ABP1 in many developmental processes. However, how crucial the role of auxin binding to ABP1 is for its functions has not been addressed. Here, we show that the auxinbinding pocket of ABP1 is essential for its gain-of-function cellular and developmental roles. In total, 16 different abp1 mutants were prepared that possessed substitutions in the metal core or in the hydrophobic amino acids of the auxin-binding pocket as well as neutral mutations.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EF - Botany
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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