Identifying craniofacial features associated with prenatal exposure to androgens and testing their relationship with brain development
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00082167" target="_blank" >RIV/00216224:14740/15:00082167 - isvavai.cz</a>
Result on the web
<a href="http://link.springer.com/article/10.1007%2Fs00429-014-0852-3" target="_blank" >http://link.springer.com/article/10.1007%2Fs00429-014-0852-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00429-014-0852-3" target="_blank" >10.1007/s00429-014-0852-3</a>
Alternative languages
Result language
angličtina
Original language name
Identifying craniofacial features associated with prenatal exposure to androgens and testing their relationship with brain development
Original language description
We used magnetic resonance (MR) images obtained in same-sex and opposite-sex dizygotic twins (n = 119, 8 years of age) to study possible effects of prenatal androgens on craniofacial features. Using a principal component analysis of 19 craniofacial landmarks placed on the MR images, we identified a principal component capturing craniofacial features that distinguished females with a presumed differential exposure to prenatal androgens by virtue of having a male (vs. a female) co-twin (Cohen's d = 0.76).Subsequently, we tested the possibility that this craniofacial "signature" of prenatal exposure to androgens predicts brain size, a known sexually dimorphic trait. In an independent sample of female adolescents (singletons; n = 462), we found that the facial signature predicts up to 8 % of variance in brain size.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.30.0009" target="_blank" >EE2.3.30.0009: Employment of Newly Graduated Doctors of Science for Scientific Excellence</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Brain Structure and Function
ISSN
1863-2653
e-ISSN
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Volume of the periodical
220
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
12
Pages from-to
3233-3244
UT code for WoS article
000361566000010
EID of the result in the Scopus database
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