Computational fluid dynamics-based design of a microfabricated cell capture device.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00082639" target="_blank" >RIV/00216224:14740/15:00082639 - isvavai.cz</a>
Result on the web
<a href="http://chromsci.oxfordjournals.org/content/53/3/411.long" target="_blank" >http://chromsci.oxfordjournals.org/content/53/3/411.long</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/chromsci/bmu110" target="_blank" >10.1093/chromsci/bmu110</a>
Alternative languages
Result language
angličtina
Original language name
Computational fluid dynamics-based design of a microfabricated cell capture device.
Original language description
A microfluidic cell capture device was designed, fabricated, evaluated by numerical simulations and validated experimentally. The cell capture device was designed with a minimal footprint compartment comprising internal micropillars with the goal to obtain a compact, integrated bioanalytical system. The design of the device was accomplished by computational fluid dynamics (CFD) simulations. Various microdevice designs were rapidly prototyped in poly-dimethylsiloxane using conventional soft lithograpy technique applying micropatterned SU-8 epoxy based negative photoresist as moulding replica. The numerically modeled flow characteristics of the cell capture device were experimentally validated by tracing and microscopic recording the flow trajectories using yeast cells. Finally, we give some perspectives on how CFD modeling can be used in the early stage of microfluidics-based cell capture device development.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/EE2.3.30.0037" target="_blank" >EE2.3.30.0037: Employment of Best Young Scientists for International Cooperation Empowerment</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Chromatographic Science
ISSN
0021-9665
e-ISSN
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Volume of the periodical
53
Issue of the periodical within the volume
3
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
411-416
UT code for WoS article
000354695600004
EID of the result in the Scopus database
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