Distinct Pattern of Gray Matter Atrophy in Mild Alzheimer?s Disease Impacts on Cognitive Outcomes of Noninvasive Brain Stimulation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F15%3A00083300" target="_blank" >RIV/00216224:14740/15:00083300 - isvavai.cz</a>
Result on the web
<a href="http://content.iospress.com/articles/journal-of-alzheimers-disease/jad150067" target="_blank" >http://content.iospress.com/articles/journal-of-alzheimers-disease/jad150067</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3233/JAD-150067" target="_blank" >10.3233/JAD-150067</a>
Alternative languages
Result language
angličtina
Original language name
Distinct Pattern of Gray Matter Atrophy in Mild Alzheimer?s Disease Impacts on Cognitive Outcomes of Noninvasive Brain Stimulation
Original language description
Background: Repetitive transcranial magnetic stimulation (rTMS) is a promising tool to study and modulate brain plasticity. Objective: Our aim was to investigate the effects of rTMS on cognitive functions in patients with mild cognitive impairment and Alzheimer?s disease (MCI/AD) and assess the effect of gray matter (GM) atrophy on stimulation outcomes. Methods: Twenty MCI/AD patients participated in the proof-of-concept controlled study. Each patient received three sessions of 10 Hz rTMS of the right inferior frontal gyrus (IFG), the right superior temporal gyrus (STG), and the vertex (VTX, a control stimulation site) in a randomized order. Cognitive functions were tested prior to and immediately after each session. The GM volumetric data of patientswere: 1)compared to healthy controls (HC) using source-based morphometry; 2) correlated with rTMS-induced cognitive improvement.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0068" target="_blank" >ED1.1.00/02.0068: Central european institute of technology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
JOURNAL OF ALZHEIMERS DISEASE
ISSN
1387-2877
e-ISSN
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Volume of the periodical
48
Issue of the periodical within the volume
1
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
10
Pages from-to
251-260
UT code for WoS article
000360931700023
EID of the result in the Scopus database
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