Methodical approaches to PCR based quantification of miRNA in epilepsy

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F16%3A00088297" target="_blank" >RIV/00216224:14740/16:00088297 - isvavai.cz</a>
Result on the web
<a href="http://www.epilepsyprague2016.org/" target="_blank" >http://www.epilepsyprague2016.org/</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Methodical approaches to PCR based quantification of miRNA in epilepsy
Original language description
microRNA(miRNA/miR) is a short noncoding RNA regulating gene expression on posttranscriptional level. The proper regulation by miRNA is essential for broad range of processes in the organism. Hence, the altered expression of miRNAs might be involved in various pathologies. Since 2010 is miRNA one of the important topics studied in the field of epilepsy. Altered miRNA profile seems to be contributing to the development of epilepsy and the disease progression. The accurate identification of miRNA profile of epilepsy and its subtypes would considerably contribute to the diagnostics and treatment of the disease. This presentation was focused on the methodical approaches used in the research of miRNA in epilepsy so far and the improvements in contemporary technologies of miRNA profiling. Recent advance in small RNA library preparation for Illumina sequencing reduces the bias in miRNA profile identification.
Czech name
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Czech description
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Project
<a href="/en/project/GA16-04726S" target="_blank" >GA16-04726S: miRNA and biochemical pathways in epilpesy</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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