Neuronal substrate and effective connectivity of abnormal movement sequencing in schizophrenia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F16%3A00088867" target="_blank" >RIV/00216224:14740/16:00088867 - isvavai.cz</a>
Alternative codes found
RIV/65269705:_____/16:00064380
Result on the web
<a href="http://www.sciencedirect.com/science/article/pii/S0278584616300033" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0278584616300033</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.pnpbp.2016.01.003" target="_blank" >10.1016/j.pnpbp.2016.01.003</a>
Alternative languages
Result language
angličtina
Original language name
Neuronal substrate and effective connectivity of abnormal movement sequencing in schizophrenia
Original language description
Movement sequencing difficulties are part of the neurological soft signs (NSS), they have high clinical value because they are not always present in schizophrenia. We investigated the neuronal correlates of movement sequencing in 24 healthy controls and 24 schizophrenia patients, with (SZP SQ+) or without (SZP SQ-) sequencing difficulties. We characterized simultaneous and lagged functional connectivity between brain regions involved in movement sequencing using psychophysiological interaction (PPI) and the Granger causality modeling (GCM), respectively. Left premotor cortex (PMC) and superior parietal lobule (SPL) were specifically activated during sequential movements in all participants. Right PMC and precuneus, ipsilateral to the hand executing the task, activated during sequential movements only in healthy controls and SZP SQ-. SZP SQ+ showed hyper-activation in contralateral PMC, as compared to the other groups.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
—
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
ISSN
0278-5846
e-ISSN
—
Volume of the periodical
67
Issue of the periodical within the volume
June
Country of publishing house
GB - UNITED KINGDOM
Number of pages
9
Pages from-to
1-9
UT code for WoS article
000371795200001
EID of the result in the Scopus database
—